Periodontitis, a common oral health problem that involves infected gums, is linked to cardiovascular disease. Scientists studying the inflammation that precedes periodontitis have found that higher inflammation, reflected by higher levels of white blood cells in saliva, is linked to less healthy arteries and a potentially higher risk of cardiovascular disease even in young, apparently healthy people.
What if we could identify the earliest warning signs of cardiovascular disease from a simple saliva sample? Scientists think they have found a way to do so. Gum inflammation leads to periodontitis, which is linked with cardiovascular disease. The team used a simple oral rinse to see if levels of white blood cells — an indicator of gum inflammation — in the saliva of healthy adults could be linked to warning signs for cardiovascular disease.
“We are starting to see more relationships between oral health and risk of cardiovascular disease,” said Ker-Yung Hong, first author of the study, now studying dentristry at the University of Western Ontario. “If we are seeing that oral health may have an impact on the risk of developing cardiovascular disease even in young healthy individuals, this holistic approach can be implemented earlier on.
Related StoriesAt the lab, participants rinsed their mouths with water before rinsing their mouths with saline which was collected for analysis. Participants then laid down for 10 minutes for an electrocardiogram, and stayed lying down for another 10 minutes so that the scientists could take their blood pressure, flow-mediated dilation, and pulse-wave velocity.
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