A record week is in a large part down to more doctors reporting cases and more tests than before.
Dr Williams added most sort throats or headaches would be common seasonal viruses, with no need to contact doctors.
It is treated with antibiotics which may also help reduce the risk of complications and spread of the bug. There have been seven cases of invasive Strep A in the past week, according to Public Health Wales - with 83 cases so far this year.
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