Exclusive: He Jiankui stops short of apologising for procedure that shocked the world of science in 2018
before moving to the US to study for a PhD at Rice University and a post-doctorate in genome sequencing at Stanford University. He returned to China in 2012 to pursue Crispr-Cas9 gene-editing research, launching a variety of biotechnology business ventures.
The edit, of a gene called CCR5, targeted a pathway used by the HIV virus to enter cells, and was claimed to give the babies immunity to HIV.Many expressed shock at the use of a risky, untested procedure in circumstances where there was no unmet medical need. He’s unpublished data indicated concerning evidence of “off-target” effects, unwanted genetic changes that can carry a risk of heart defects, cancer and developmental problems.
When asked about how the third child was doing, He replied: “I’m not answering this question,” later adding that the child was “living a normal life living with their parents”. “According to Chinese law, when a person has served the prison [sentence], after that they begin again with full rights,” he said. “Compared to the past experience, it’s more important what we’re doing today that determine whether I move on or not.”
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