Scientists discover how to ‘switch off’ fear in the brain – all thanks to a 5p pill ...

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Scientists discover how to ‘switch off’ fear in the brain – all thanks to a 5p pill ...
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Credit: Spitzer Lab, UC San Diego“The benefit of understanding these processes at this level of molecular detail — what is going on and where it’s going on — allows an intervention that is specific to the mechanism that drives related disorders.“Now that we have a handle on the core of the mechanism by which stress-induced fear happens and the circuitry that implements this fear, interventions can be targeted and specific.

They found putting the mice under stress caused the chemical signals in the brain cells to change, producing the generalised fear response.When mice were treated with fluoxetine immediately after a stressful event, the change did not occur. But researchers said the drug had no effect after the change occurs, which is why antidepressants do not work for all PTSD patients.

They said the findings are a promising start down a path that could lead to more effective treatments.Re-experiencing is the most typical symptom of PTSD.Some people have constant negative thoughts about their experience, repeatedly asking themselves questions that prevent them coming to terms with the event.

For example, they may wonder why the event happened to them and if they could have done anything to stop it, which can lead to feelings of guilt or shame.

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