San Francisco 49ers fans mark your calendars as the team's home opener was announced Thursday.
fans mark your calendars as the team dropped their schedule for the 2022 regular season Thursday.
The Niners will then face the rival Seattle Seahawks in their home opener in Week 2 on Sept. 18. The game airs on FOX at 1:05 p.m. Fast-forward to Week 11 of the season the 49ers will see the Arizona Cardinals on Nov. 21. Fans who want to catch the game in person will have to travel to Azteca Stadium in Mexico City.
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