Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research.
Prior vaccination against tetanus and diphtheria, with or without pertussis ; herpes zoster , better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston..
"We were wondering whether the influenza finding was specific to the flu vaccine. This data revealed that several additional adult vaccines were also associated with a reduction in the risk of Alzheimer's," said Schulz, who is the Umphrey Family Professor in Neurodegenerative Diseases and director of the Neurocognitive Disorders Center at McGovern Medical School.
"By leveraging modern data analysis models and the very large claims database subscribed by McWilliams School of Biomedical Informatics, we gained valuable insights into which vaccines may protect against Alzheimer's and potentially develop more effective prevention strategies," said Xiaoqian Jiang, PhD, a co-author on the study who holds the Christopher Sarofim Family Professorship in Biomedical Informatics and Bioengineering with McWilliams School of Biomedical Informatics.
Bukhbinder, Harris, Jiang, Ling, and Schulz recently explored the possible mechanisms in an article inBukhbinder said the research provides unique insights on the possible impact of certain vaccine technologies in the protection against Alzheimer's disease.
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