Researchers use integrated imaging data to identify sex-specific brain signatures driving obesity. A study discovered sex-specific brain signals that affect obesity development, with women's obesity linked to emotion-related eating and men's eating behavior influenced by gut sensations. The findi
A UCLA study published in Brain Communications has identified sex-specific brain signals that influence obesity development in men and women. By combining MRI data with clinical features and personal histories, researchers found differences in several brain networks associated with early life adversity, mental health quality, and sensory stimulation experiences.
The new study supports and corroborates many findings from that and earlier studies and provides MRI evidence of differences in brain structure, function, and connectivity that may help researchers better understand obesity-related drives and behaviors. For example, alterations in certain brain networks suggest that compared to men, women with a high body mass index may be more keenly aware of and drawn to highly processed foods, with an increased risk of developing cravings and food addiction.
Each participant also underwent three different brain MRIs to assess structure, function and connectivity. Data sets from the three scans and from clinical information were analyzed using an analytical tool that seeks to identify a limited number of variables from multiple data sets to predict an outcome.
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