Muscle-mass preservation is becoming a hot new area in obesity medicine.
Ania Jastreboff, director of the Yale Obesity Research Centre who has led key Mounjaro studies for Lilly, said at a conference that improving the quality — not just the quantity — of weight loss was an essential next-step.
Experts aren’t clear on just how big of a problem this is for older people taking diabetes and weight-loss drugs such as Mounjaro and Wegovy. In a clinical trial of semaglutide, researchers found that on average, people lost about 6.8 kilograms of lean muscle and 10.4 kilograms of fat during a 68-week trial. The average age in that group of people was 52.
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