Sites and landmarks including the Dartford Crossing and Brighton Pier will be lit up in blue.
Health minister Maria Caulfield said the NHS would be "thriving" in 25 years' time despite warnings from experts about its long term future.in disputes over pay.
Ms Caulfield, who is the MP for Lewes and also a nurse, said: "I've worked in the NHS for over 30 years of its 75 years. I've seen tremendous change and I think, through my lifetime of working in the NHS, people have always been very sceptical about its future."
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