Researchers develop first-of-its-kind adhesive bandage that uses gold nanoparticles to detect COVID-19 antibodies
. Briefly, a plate reader was used to measure the concentration of hemoglobin in plasma samples separated using the filter paper of the HFA or centrifugation . The plasma separation efficiency was then calculated using:where Abs , Abs , and Abs are respective absorbance values as measured from optical densities at 412 nm, 407 nm, and 575 nm.
The supernatant was discarded, and the pellets were resuspended in 200 µL solutions of potassium carbonate or disodium phosphate. An additional 20 µL of Trizma base was added to the AuNP-N solution for increased stability. Control AuNP-IgE bioconjugates were prepared similarly using 10 µg mLAuNP bioconjugates were characterized using a UV-2700 spectrophotometer to record changes in the absorbance spectra of AuNPs before and after each step of functionalization.
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