Study linking mucus plugs and COPD mortality could help save lives brighamwomens JAMA_current
plugs, an accumulation of mucus in the lungs that can affect quality of life and lung functioning. A new study led by researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, has found that mucus plugs were also associated with greater mortality.
"For the last four decades we've had only two targets for COPD therapies –either promoting bronchial dilation, which means making the airways themselves wider, or reducing bronchial inflammation," said Diaz."This is telling us that there may be more we can do about this disease than we realized before."
The researchers found that over the course of the study, the mortality rate for COPD patients with no detectable mucus plugs was 34 percent. For patients with mucus plugs in up to two lung segments, the mortality rate jumped to 46.7 percent. For patients with plugs in three or more lung segments, the mortality rate was 54.1 percent.
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