Cancer research took intriguing new turns last year, from advances that could speed vaccines to immunotherapy that secured a decade of remission
in 2017, but the technology has since become one of the most promising treatments for a variety of cancers. CAR-based therapies involve removing a person’s immune cells and genetically engineering them to better recognize and fight cancer before infusing them back into the body. In 2010, two patients with blood cancer received a form of CAR T-cell therapy; now, a decade later, those patients are still in remission.
to create a new gradient or, in some cases, by softening the cells around them, resulting in a gradient of stiffness. Such movement has since been implicated in everything from cancer progression to immune cell migration to embryonic development; it may have implications for therapies designed to draw cancerous cells into areas where they’re more vulnerable. “It’s now seen everywhere, suddenly,” says Jonna Alanko, a postdoc at the Institute of Science and Technology Austria.
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