The maternal and perinatal outcomes of pregnancies complicated by monkeypox infection StGeorgesUni LivUni pregnancy infection monkeypox perinatal
Introduction The monkeypox virus is an orthopoxvirus, just like smallpox and cowpox viruses. It has caused multiple outbreaks over the last couple of decades. More recently, a much larger outbreak occurred in developed countries in Europe and North America, none of which were known to be endemic to the disease.
Smallpox in pregnancy is known to cause a much higher case fatality rate, especially in the third trimester. With this in mind, the authors of the current study, posted online in the American Journal of Obstetrics and Gynecology MFM, focused on the outcomes of monkeypox in pregnancy. They observed outcomes such as fetal loss, neonatal or perinatal death, fetal anomalies, preterm birth, maternal illness requiring hospitalization, maternal deaths, and vertical transmission.
Related StoriesTwo-thirds of infected pregnancies were affected by fetal loss, in the first trimester, vs. 82% in the second trimester, clearly showing the deleterious effect of monkeypox infection in pregnancy irrespective of the stage of fetal development. What are the conclusions? The findings from this systematic review, limited by the very small number of included cases, suggest a high rate of miscarriage and perinatal loss in people with monkeypox infection in pregnancy.”
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