Why is there no RSV vaccine?
Hospitals around the country are reporting surges in RSV cases, like Blank Children's Hospital in Des Moines, Iowa, which registered 165 pediatric patients to ER in a 24-hour period on Saturday—a new record, according to KCCI News. Meanwhile St. Luke's Children's Hospital in Idaho was at capacity for pediatric patients on Sunday, according to KTVB News.Failure Spooked Vaccine Makers
In 1966, a Washington, D.C. trial of an RSV vaccine had the opposite of its intended effect, sending 80% of test children to the hospital with severe respiratory disease.Most scientists blame formalin, a chemical used to inactivate RSV in the vaccine that could have produced weak antibodies. These weak antibodies could have set back the children's ability to fight off the virus.
Although there is no vaccine for RSV, that could change as early as next fall. After decades of failure, a new RSV vaccine is finally showing promise when given toPfizer announced earlier this year that their new vaccine is 82% effective at preventingwithin the first 90 days of being born. Known as "RSVpreF," this vaccine showed no safety concerns at trial for either mother or child.
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