If you've been having a bit too much fun this weekend and are in need of something to challenge you, why not try out a difficult brainteaser?
If you've been having a bit too much fun this weekend and are in need of something to challenge you, why not try out a difficult brainteaser?
With that in mind, here's a brain teaser that has left people scratching their heads in confusion, as it's particularly difficult to solve. The Mirror reports all you have to do is find the number hidden among the polka dots, which sounds simple enough. Can you see it? Try and find it within nine seconds or less, and you could be on track to call yourself a genius.
Australia Latest News, Australia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Roles of bile acids signaling in neuromodulation under physiological and pathological conditions - Cell & BioscienceBile acids (BA) are important physiological molecules not only mediating nutrients absorption and metabolism in peripheral tissues, but exerting neuromodulation effect in the central nerve system (CNS). The catabolism of cholesterol to BA occurs predominantly in the liver by the classical and alternative pathways, or in the brain initiated by the neuronal-specific enzyme CYP46A1 mediated pathway. Circulating BA could cross the blood brain barrier (BBB) and reach the CNS through passive diffusion or BA transporters. Brain BA might trigger direct signal through activating membrane and nucleus receptors or affecting activation of neurotransmitter receptors. Peripheral BA may also provide the indirect signal to the CNS via farnesoid X receptor (FXR) dependent fibroblast growth factor 15/19 (FGF15/19) pathway or takeda G protein coupled receptor 5 (TGR5) dependent glucagon-like peptide-1 (GLP-1) pathway. Under pathological conditions, alterations in BA metabolites have been discovered as potential pathogenic contributors in multiple neurological disorders. Attractively, hydrophilic ursodeoxycholic acid (UDCA), especially tauroursodeoxycholic acid (TUDCA) can exert neuroprotective roles by attenuating neuroinflammation, apoptosis, oxidative or endoplasmic reticulum stress, which provides promising therapeutic effects for treatment of neurological diseases. This review summarizes recent findings highlighting the metabolism, crosstalk between brain and periphery, and neurological functions of BA to elucidate the important role of BA signaling in the brain under both physiological and pathological conditions.
Read more »
Scots teen left with swelling on brain after Zante bouncer 'attacked' himConor King, 18, lay unconscious on the ground for around 15 minutes before being rushed to a Greek hospital by ambulance in the early hours of June 15.
Read more »
Stem cell model of human brain development suggests embryonic origins of Alzheimer's diseaseAlzheimer's disease (AD) mainly affects the older population. Recent research found early disease signs in cell culture models of early human brain development, raising the possibility that the disease has its origins much earlier in life, possibly during embryogenesis—the formation and development of an embryo.
Read more »
For all the brain benefits, you won’t catch me napping\n\t\t\tLet our global subject matter experts broaden your perspective with timely insights and opinions you\n\t\t\tcan’t find anywhere else.\n\t\t
Read more »
Young Scots dad who battled brain cancer twice given heartbreaking news at scanA young Edinburgh dad who has already been through two cancer battles received heartbreaking news from doctors at his most recent scan
Read more »