UC San Diego School of Medicine and Salk Institute for Biological Studies researchers have created an atlas of the amygdala, a structure within the brain that\u2026
An estimated 4.8 million people used cocaine in 2021, while 1.4 million people had a cocaine use disorder, according to the National Institute on Drug AbuseSchool of Medicine and Salk Institute for Biological Studies researchers have created an atlas of the amygdala, a structure within the brain that plays a crucial role in controlling emotional responses to drugs, it was announced Thursday.
According to the National Institute on Drug Abuse, an estimated 4.8 million people used cocaine in 2021, while only 1.4 million people had a cocaine use disorder."Some people use cocaine recreationally and never develop an addiction, while others are extremely susceptible to addiction after very little exposure to the drug or may relapse even after years of abstinence," Telese said.
"The cocaine brain bank is an exceptional resource and was invaluable for this study because it allowed us to study a cohort of rats with a large amount of genetic variety, which mimics the diversity we see in human populations," Telese said."Further, using a model of cocaine addiction where rats administered the drug to themselves let us look at the connection between our molecular discoveries and actual addiction behaviors.
Jess Zhou, a UCSD graduate student working with McVicker, developed the workflow needed to assemble their sequencing data into a molecular atlas of the rat amygdala, the statement read.
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