Team of experts from UK, US and Singapore to design jab to save thousands of lives by rewriting DNA
Photograph: British Heart Foundation/PAPhotograph: British Heart Foundation/PAScientists are to develop the world’s first cure for genetic heart conditions by rewriting DNA in a move hailed as a “defining moment” for cardiovascular medicine.
“This is a defining moment for cardiovascular medicine,” said Prof Sir Nilesh Samani, the BHF’s medical director. All those with genetic cardiomyopathies have a 50/50 risk of passing faulty genes on to each of their children and, often, several members of the same family develop heart failure, need a heart transplant, or die at a young age.
Under the new programme of research, experts hope to permanently correct or silence mutant genes involved in causing these heart problems.Christine Seidman, a professor of medicine at Harvard Medical School in the US and co-lead of the CureHeart project, said the idea was to “fix the hearts” and revert them to more normal function.
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