For people with severe alcohol use disorder, a new gene therapy trial could lead to an effective treatment that would involve chemically rebalancing the area of the brain associated with addiction.
Woods said it's important to remember the science behind why addiction occurs.
"Up until 1980 or so, people thought that addiction was essentially a moral failure, and then somewhere I would say around 1980 or so, medicine came around and said, 'Not so fast.' Medicine said that addictions very much are chronic relapsing illnesses like diabetes,"And the true cause of addiction are these biological, psychological and social forces. And when these forces come together, they change something in the brain, if you will. They flip the brain switch on.
Grant is hopeful that, after more rounds of testing, her team's study will eventually lead to a new and effective treatment for severeStill,"we want to be really careful in overstating or generalizing the other addictions," she noted."In particular, it would have to be carefully studied for any kind of stimulant
because that is so involved directly in the dopamine pathways. We think there might be generalization to some addictions, but there could be more adverse effects with other types of drugs that a person might be using chronically."
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