Is there an association between migraines and the onset of inflammatory bowel disease? researchsquare migraines inflammatoryboweldisease IBD IBS gutbrainaxis
By Neha MathurAug 4 2023Reviewed by Lily Ramsey, LLM In a recent article posted to the Research Square* preprint server, researchers used the National Health Insurance Service data of 10,628,070 Koreans aged ≥20 to investigate the link between migraines and the new onset of inflammatory bowel disease , a chronic gastrointestinal disorder, including Crohn's disease and ulcerative colitis .
Background Studies have shown that the incidence and prevalence of IBD have increased in South Korea. Thus, researchers aim to identify risk factors modifiable before the onset of IBD. Related StoriesThey followed up with these participants for a median of 10.3 years to determine the incidence rates of IBD per 100,000 person-years. The team defined patients with IBD by ICD-10 and a special V code constituting the rare intractable disease code used by NHIS since 2006.
Results The main study finding was that patients with migraine were at an increased risk of developing IBD, including CD and UC. The cumulative risk of IBD, especially CD, showed a steep rise up to five years following a diagnosis of migraine.
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