Microdosing: Scientists tackle psychedelic trend becoming ‘creative enhancer of choice’

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Microdosing: Scientists tackle psychedelic trend becoming ‘creative enhancer of choice’
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Microdosing: Scientists tackle psychedelic trend becoming ‘creative enhancer of choice’ | JewelTopsfield

, found good evidence across both survey and controlled lab studies that psychedelic microdoses can reduce pain, alter the perception of time and cause noticeable changes to conscious awareness.

Less than half of the studies the pair reviewed were placebo controlled, for example. Of those with placebos, many participants accurately guessed they had consumed a psychedelic drug, which meant it was impossible to tease apart the influence of expectation and drug effects.

The paper makes recommendations for the emerging field, including longitudinal studies, trials using active placebo controls , diverse participants rather than enthusiastic microdosing volunteers, and more research into the safety of microdosing. “Some of the self-report data is really quite compelling,” Polito says. “One study showed that just over half of people taking traditional antidepressants stopped taking them after they started microdosing.”

“I don’t think it’s a nothing burger. And I don’t predict that it will turn out to be all expectancy,” he says.

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