Study examines the reinfection of SARS-CoV-2 variants in children OhioState reinfection covid COVID19 SARSCoV2 infection virology immunology microbiology virus research childrenshealth
By Tarun Sai LomteMay 3 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Journal of the Pediatric Infectious Diseases Society, researchers characterized the children with severe acute respiratory syndrome coronavirus 2 reinfection, determined the number of reinfections, and characterized the intervals between two infections in the patient population.
About the study In the present study, researchers characterized SARS-CoV-2 reinfections in children. Individuals aged 21 or younger testing SARS-CoV-2-positive by nucleic acid amplification or antigen testing between March 14, 2020, and September 30, 2022, at any area of the Nationwide Children’s Hospital system were included.
When samples were unavailable , the predominant SARS-CoV-2 variant at sampling was assumed to be present in specimens. Demographic data, testing site, and hospitalization and vaccination status were obtained from electronic health records . EHRs were available/accessible for 529 patients. Most patients had an underlying condition, with chronic respiratory distress being the most prevalent at 16%.
Three patients had samples available from first and second infections for variant typing. They were infected with SARS-CoV-2 Delta and later by Omicron BA.1 within 90 days. Over 1,800 samples were tested for variant surveillance.
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