UQ's COVID vaccine technology finally moves to human trial phase after 2020 false start

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UQ's COVID vaccine technology finally moves to human trial phase after 2020 false start
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A human trial has been launched into the University of Queensland's second-generation COVID vaccine, more than two years after the original technology was abandoned amid patients falsely testing positive to HIV.

abc.net.au/news/covid-vaccine-human-trials-university-of-queensland-medical/102105340A human trial has been launched into the University of Queensland's second generation COVID vaccine, more than two years after the original technology was abandoned amid patients falsely testing positive to HIV.

"Our primary purpose is not to bring another COVID vaccine to market," Associate Professor Chappell said. "This isn't going to be the last time the world faces a pandemic and next time around, we want to … make sure there are doses available as quickly as possible and they're safe, and they can protect Australians and people around the world.

That worked by allowing the immune system to recognise – and attack – the spike protein, producing protective antibodies. Professor Chappell said the fragments of protein in HIV had been replaced by a "small amino acid sequence with similar properties" in Clamp2."We had to go right back to square one to define something that had the right properties to be a molecular clamp," Professor Chappell said.

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