US comedian Pat Cooper, best known for his roles in Analyze This and Seinfeld, has died aged 93.
The star was well known for his regular appearances on TV and radio, particularly on The Howard Stern Show.
'I put out a lot of the fires! He was one man who was honest. You could depend on him. You could trust him.Cooper was a legend in the comedy scene and appeared in an episode of Seinfeld
Australia Latest News, Australia Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Irish rugby star marries Derry model Joanna Cooper in luxury Algarve resortThe former Miss Universe Ireland winner wore a dress from a Magherafelt bridal store for big day in Portugal
Read more »
The challenges Intel faces to compete with TSMC, SamsungFabs still need to be built, process tech needs to be proven – and Pat's gotta make it price competitive
Read more »
Rachel Reeves orders Shadow Cabinet not to make unfunded spending promises before next electionSir Keir Starmer and Rachel Reeves have formally ordered the Shadow Cabinet not to make any unfunded spending pledges ahead of the next general election, theipaper can reveal 🔴 Exclusive from paulwaugh
Read more »
Fine-tuning 3D lab-grown mini tumors to help predict how patients respond to cancer therapiesScientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.
Read more »
Progesterone: A Neuroprotective Steroid of the IntestineThe enteric nervous system (ENS) is an intrinsic network of neuronal ganglia in the intestinal tube with about 100 million neurons located in the myenteric plexus and submucosal plexus. These neurons being affected in neurodegenerative diseases, such as Parkinson’s disease, before pathological changes in the central nervous system (CNS) become detectable is currently a subject of discussion. Understanding how to protect these neurons is, therefore, particularly important. Since it has already been shown that the neurosteroid progesterone mediates neuroprotective effects in the CNS and PNS, it is now equally important to see whether progesterone has similar effects in the ENS. For this purpose, the RT-qPCR analyses of laser microdissected ENS neurons were performed, showing for the first time the expression of the different progesterone receptors (PR-A/B; mPRa, mPRb, PGRMC1) in rats at different developmental stages. This was also confirmed in ENS ganglia using immunofluorescence techniques and confocal laser scanning microscopy. To analyze the potential neuroprotective effects of progesterone in the ENS, we stressed dissociated ENS cells with rotenone to induce damage typical of Parkinson’s disease. The potential neuroprotective effects of progesterone were then analyzed in this system. Treatment of cultured ENS neurons with progesterone reduced cell death by 45%, underscoring the tremendous neuroprotective potential of progesterone in the ENS. The additional administration of the PGRMC1 antagonist AG205 abolished the observed effect, indicating the crucial role of PGRMC1 with regard to the neuroprotective effect of progesterone.
Read more »
Love Island’s Maya Jama reveals which Spider-Man actor 'loves the show''He’s a big fan.'
Read more »